How much should I expect to pay for Humalog U-100?

Prescription drug prices can be confusing. Two people may pay different prices for the same drug, depending on their insurance situation.

The list price1 of a 5-pack of 3 mL Humalog U-100 KwikPens (15 mL or 15,000 units) is $530.40 and the list price of a Humalog U-100 10 mL (10,000 units) vial is $274.70, but the amount you pay will largely depend on your prescription drug insurance plan. Insulin needs vary significantly from person to person, some take only 5 units per meal while others take over 100 units per meal. Given this variability, providing a relevant average cost for a month’s supply of Humalog U-100 is difficult. The information below will give you a good idea of what to expect based on your insurance and support that may be available to you.

For the most accurate information, talk to your insurance provider who knows the details of your plan.

Which Option Below Best Describes Your Insurance Situation?

About 80% of Humalog U-100 prescriptions cost between $0 and $30 per month, and the remaining cost an average of $135 (vial) or $130 (5-pack KwikPens) per month.2

What you pay for Humalog U-100 will depend on your insurance plan. Each plan has different preferred drug lists and out-of-pocket amounts, and most include an annual deductible. If you haven't met your deductible, you'll see higher prices and could pay full retail price until you meet your deductible.

For personalized assistance on the most affordable options for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday-Friday, 9 a.m. to 8 p.m. Eastern Time.

For most patients with Medicare Part D coverage, out-of-pocket costs can vary throughout the year depending on which phase of the Part D benefit you are currently in. About 75% (vial) or 78% (5-pack KwikPens) of Humalog U-100 prescriptions cost between $0 and $100 a month, and the remaining cost an average of $178 (vial) or $187 (5-pack KwikPens) per month.2

Some Medicare patients qualify for extra financial support through the Extra Help3 program. If you are eligible for Extra Help, you can expect to pay $3 to $9 for each prescription.4

If you are unsure whether you qualify for Extra Help and would like more information, please visit: https://www.ssa.gov/benefits/medicare/prescriptionhelp/.

For personalized assistance on the most affordable options for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday-Friday, 9 a.m. to 8 p.m. Eastern Time.

For most people on Medicaid, out-of-pocket costs for prescription drugs like Humalog U-100 range from $4 to $9 per month.5 Some states allow even lower copays or eliminate the copay requirement altogether.

To find out if you qualify for Medicaid, or for more information about copayments in your state, please visit: https://www.medicaid.gov/state-overviews/index.html.

For personalized assistance on the most affordable options for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday-Friday, 9 a.m. to 8 p.m. Eastern Time.

If you do not have prescription drug coverage6 or if your insurance does not cover Humalog, you can expect to pay close to the list price shown above, plus any additional pharmacy charges depending on where you purchase your medicine.

For personalized assistance on the most affordable options for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday-Friday, 9 a.m. to 8 p.m. Eastern Time.

Want More Information?

For personalized assistance on the most affordable options for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday-Friday, 9 a.m. to 8 p.m. Eastern Time. Although we won't replace the advice of your healthcare provider, we'll do our best to help find affordable options for you.

Need Another Option?

Lilly donates medicines to the Lilly Cares Foundation, a separate nonprofit organization that helps qualified people in need receive Lilly medicines at no cost. Learn more at www.lillycares.com or by calling Lilly Cares at 1-800-545-6962.

1 List price, also referred to as wholesale acquisition cost or WAC, is the price at which Lilly sells its products to wholesalers and may not represent actual transactional prices patients pay at the pharmacy. 2019. AnalySource accessed on July 3, 2019. Reprinted with permission by First Databank, Inc. All rights reserved. ©2019. https://www.fdbhealth.com/policies/drug-pricing-policy/

2 Source: Based on internal analysis of IQVIA Longitudinal Access and Adjudication Data (LAAD) – Humalog U-100 Patient OOP Cost per Script by Channel (April 2018 – March 2019). Accessed on July 26, 2019. Employer or Private Individual Policy Insurance reflects commercial savings card and other support. Medicare Part D Coverage reflects supplemental support.

3 Social Security Administration (SSA). Extra Help with Medicare Prescription Drug Plan Costs. https://www.ssa.gov/benefits/medicare/prescriptionhelp/. Accessed on July 24, 2019.

4 Centers for Medicare & Medicaid Services (CMS). Announcement of Calendar Year (CY) 2019 Medicare Advantage Capitation Rates and Medicare Advantage and Part D Payment Policies and Final Call Letter. Attachment V Final 2019 Benefit Design Parameters. https://www.cms.gov/Medicare/Health-Plans/MedicareAdvtgSpecRateStats/Downloads/Announcement2019.pdf. Accessed on July 24, 2019.

5 Centers for Medicare & Medicaid Services (CMS). Medicaid and CHIP Overview for Assisters. Maximum Allowable Copayments Determined by Eligible Population's Household Income. Updated August 2018. **All out-of-pocket charges are based on the specific state's defined payment amount for that service. Certain groups, including children, terminally ill individuals, and individuals residing in an institution are exempt from cost sharing. Refer to yourstate agency for details about Medicaid out-of-pocket costs. https://marketplace.cms.gov/technical-assistance-resources/fast-facts-medicaid-chip.pdf. Accessed on July 24, 2019.

6 Most people have some type of health insurance coverage that includes a prescription drug benefit. According to recent data, just under 9% of the total U.S. population is uninsured. https://www.kff.org/state-category/health-coverage-uninsured/health-insurance-status/.

Indication and Important Safety Information
Indication for Humalog®

Humalog is used to treat people with diabetes for the control of high blood sugar.

Important Safety Information for Humalog

What is the most important information I should know about Humalog?

  • Do not share your Humalog KwikPen, Humalog Junior KwikPen, cartridges, reusable pen compatible with Lilly 3 mL cartridges, or syringes with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
  • Do not change the insulin you use without talking to your healthcare provider. Changes may make you more likely to experience low or high blood sugar. Changes should be made cautiously under the supervision of your healthcare provider.
  • Test your blood sugar levels as your healthcare provider instructs.
  • Your insulin dose may need to change because of illness, stress, other medicines you take, change in diet, or change in physical activity or exercise.
  • When used in a pump, do not mix or dilute Humalog with any other insulin or liquid.
Who should not take Humalog?
  • Do not take Humalog if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in Humalog.
Before using Humalog, what should I tell my healthcare providers?
  • About all of your medical conditions, including liver, kidney, or heart failure or other heart problems.
  • If you are pregnant, planning to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription (especially ones commonly called TZDs [thiazolidinediones]) and nonprescription medicines, vitamins, and herbal supplements.
How should I use Humalog?
  • Humalog is a rapid-acting insulin. Take Humalog within fifteen minutes before eating or right after eating a meal.
  • Always make sure you receive the correct type of Humalog from the pharmacy.
  • Do not use Humalog if it is cloudy, colored, or has solid particles or clumps in it.
  • Inject Humalog under your skin (subcutaneously). Never inject into a vein or muscle. Change (rotate) your injection site with each dose. Make sure you inject the correct insulin and dose.
  • Do not re-use needles. Always use a new needle for each injection. Re-use of needles can cause you to receive the wrong dose of Humalog and result in infection.
  • Do not drive or operate heavy machinery until you know how Humalog affects you. Do not use alcohol while using Humalog.
What are the possible side effects of Humalog?
  • Severe low blood sugar can cause unconsciousness (passing out), seizures, and death. Low blood sugar is the most common side effect. There are many causes of low blood sugar, including taking too much Humalog. It is important to treat it quickly. You can treat mild to moderate low blood sugar by drinking or eating a quick source of sugar right away. Symptoms may be different for each person. Be sure to talk to your healthcare provider about low blood sugar symptoms and treatment.
  • Severe life-threatening allergic reactions (whole-body reactions) can happen. Get medical help right away if you develop a rash over your whole body, have trouble breathing, have a fast heartbeat, or are sweating.
  • Humalog can cause life-threatening low potassium in your blood (hypokalemia), which can cause severe breathing problems, irregular heartbeat, and death.
  • Serious side effects can include swelling of your hands and feet and heart failure when taking certain pills called thiazolidinediones or “TZDs” with Humalog. This may occur in some people even if they have not had heart problems before. Tell your healthcare provider if you have shortness of breath, swelling of your ankles or feet, or sudden weight gain, which may be symptoms of heart failure. Your healthcare provider may need to adjust or stop your treatment with TZDs or Humalog.
  • Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in case of pump failure.
  • The most common side effects of Humalog include low blood sugar, allergic reactions, including reactions at your injection site, skin thickening or pits at the injection site (lipodystrophy), itching, and rash. These are not all of the possible side effects. Ask your healthcare provider for more information or for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Humalog is available by prescription only.

For additional information, talk to your healthcare providers and please click to access Humalog Full Prescribing Information and Patient Prescribing Information.

Please see Instructions for Use included with the Humalog KwikPen.

HUMALOG HI CON ISI 06JUN2017