Through Lilly’s Insulin Value Program, anyone with Employer/Private Insurance or no insurance can fill their monthly prescription for Lilly insulins for $35. Call the Lilly Diabetes Solution Center at (833) 808-1234 for more information.

How much should I expect to pay for a Lilly Non-Branded Insulin?

Prescription drug prices can be confusing. Two people may pay different prices for the same drug, depending on their insurance situation.

The list price1 is for each of the following:

  • 5-pack of 3 mL Insulin Lispro Injection U-100 KwikPens (15 mL or 1,500 units)
  • 5-pack of 3 mL Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPens (100 units/mL)
  • 5-pack of 3 mL Insulin Lispro Injection Junior KwikPens (100 units/mL)

The list price1 is for:

  • a 10 mL Insulin Lispro U-100 vial

Most people do not pay the list price. The amount you pay depends on your prescription drug insurance plan. Insulin needs vary significantly from person to person. Given this variability, providing a relevant average cost for a month’s supply of insulin is difficult. For the most accurate information, talk to your insurance provider who knows the details of your plan.

Find Out if a Lilly Non-Branded Insulin is Right for You

Lilly’s Non-Branded Insulins are lower list-priced insulin options to the branded Humalog insulin that may help lower out-of-pocket costs. When you pick up your prescription, your pharmacist will help evaluate which is the least expensive option for you. For many people with commercial drug insurance, Lilly's Humalog branded insulin may still have a lower out-of-pocket cost than Lilly's Non-Branded Insulins.

If you are in a high deductible period, you should ask your pharmacist which is the lower-cost option for you.

Individuals should consider formulary status of all medications they may be taking when making enrollment decisions. Only your insurance provider or pharmacist will be able to determine the most cost-effective option for you.

Don’t Have Insurance?

If you do not have prescription medication insurance coverage, you should ask your pharmacist which is the lower-cost option for you.

If you are interested in obtaining insurance, there are resources available to help you:

See below for information regarding additional support services that may be available to you.

Lilly Diabetes Solution Center

Want to Learn More?

To learn more about Lilly’s Non-Branded Insulins, call the Lilly Diabetes Solution Center at (833) 808-1234.

NOTE: The Lilly Diabetes Solution Center will not be able to determine which is the most cost-effective option for you. For the most accurate information, talk to your insurance provider who knows the details of your plan.

1 List price, also referred to as wholesale acquisition cost or WAC, is the price at which Lilly sells its products to wholesalers and may not represent actual transactional prices patients pay at the pharmacy. WAC from AnalySource accessed on . Reprinted with permission by First Databank, Inc. All rights reserved. .


Warnings -

Do not take Humalog or Insulin Lispro Injection if you have:

  • symptoms of low blood sugar (hypoglycemia)
  • an allergy to insulin lispro products or any of their ingredients.

Do not reuse needles or share your insulin injection supplies with other people. This includes your:

  • prefilled pen for use by a single patient
  • cartridges
  • reusable pen that works with Lilly 3mL cartridges
  • needles
  • syringes

You or the other person can get a serious infection. This can happen even if you change the needle.

Do not change the type of insulin you take or your dose, unless your doctor tells you to. This could cause low or high blood sugar, which could be serious.

Do not use a syringe to remove Humalog from your prefilled pen. This can cause you to take too much insulin. Taking too much insulin can lead to severe low blood sugar. This may result in seizures or death.

Humalog and Insulin Lispro Injection may cause serious side effects. Some of these can lead to death. The possible serious side effects are:

  • Low blood sugar. This can cause:
    • dizziness or light-headedness
    • headache
    • shakiness
    • irritability
    • sweating
    • blurred vision
    • fast heartbeat
    • mood change
    • confusion
    • slurred speech
    • anxiety
    • hunger

    If you are at risk of having severely low blood sugar, your doctor may prescribe a glucagon emergency kit. These are used when your blood sugar becomes too low and you are unable to take sugar by mouth. Glucagon helps your body release sugar into your bloodstream.

  • Severe allergic reaction.

    Get emergency help right away if you have:

    • a rash over your whole body
    • sweating
    • extreme drowsiness
    • swelling of your face, tongue, or throat
    • trouble breathing
    • a faint feeling
    • dizziness
    • a fast heartbeat
    • shortness of breath
    • confusion
  • Low potassium in your blood. This can lead to severe breathing problems, irregular heartbeat, and death.
  • Heart failure. Taking diabetes pills called thiazolidinediones (thIE-uh-zOH-li-dEEn-dIE-OHns), or “TZDs,” with insulin lispro products may cause heart failure in some people. This includes people who do not have any heart problems. If you have heart failure, it may get worse if you take TZDs with these insulin lispro products. Tell your doctor if you have any new symptoms of heart failure, or if they get worse. Some symptoms of heart failure include: shortness of breath, swelling of ankles and feet, and sudden weight gain. Your doctor may need to change or stop treatment with TZDs and your insulin lispro product.
  • High blood sugar and ketoacidosis. You can have these serious problems when your insulin pump or infusion set stops working. They can also happen if your insulin is no longer effective. For these reasons, always keep extra insulin injection supplies with you.

Common side effects

The most common side effects of Humalog and Insulin Lispro Injection are:

  • low blood sugar
  • reactions where you have injected insulin
  • swelling of your hands or feet
  • itching
  • allergic reactions
  • changes in fat tissue where you have injected insulin
  • weight gain
  • rash

These are not all of the possible side effects. Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or

Before using

Talk with your doctor about low blood sugar and how to manage it. Also tell your doctor:

  • about all of the medicines you take, including over-the-counter medicines, vitamins, and herbal supplements.
  • about any other prescription medicines you take, especially ones called TZDs.
  • about all of your medical conditions, including if you have heart failure or other heart, liver, or kidney problems.
  • if you are pregnant, breastfeeding, or plan to become pregnant or breastfeed.

How to take

Read the Instructions for Use that come with your Humalog or Insulin Lispro Injection. Be sure to take your insulin lispro product and check your blood sugar levels exactly as your doctor tells you to. Your doctor may tell you to change your dose because of illness, increased stress, or changes in your weight, diet, or physical activity level. He or she may also tell you to change the amount or time of your dose because of other medicines or different types of insulin you take.

Before injecting your insulin lispro product

You can inject your insulin dose yourself, or you can have a trained caregiver inject it for you. Make sure you or your caregiver:

  • Check the insulin label before each injection. This will help you make sure that you are taking the correct insulin.
  • Use a new needle for each injection. You can get a serious infection or the wrong dose of insulin if you re-use needles.
  • Change (rotate) where you inject your insulin with each dose. This can reduce your chance of getting pits, lumps, or thickened skin where you inject your insulin. Do not inject your insulin into the exact same spot or where the skin has pits or lumps. Avoid injecting into thickened, tender, bruised, scaly, hard, scarred, or damaged skin.

When you are ready to inject

  • Inject Humalog or Insulin Lispro Injection, under your skin within 15 minutes before or right after you eat a meal.

Staying safe while taking your insulin lispro product

To stay safe while taking your insulin, be sure to never inject Humalog U-200 in your vein, muscle, or with an insulin pump. Also be sure not to:

  • mix Humalog U-200 with other insulins or liquids.
  • drive or use heavy machinery until you know how your insulin lispro product affects you.
  • drink alcohol or use other medicines that contain alcohol when taking your insulin lispro product.

Learn more

Humalog and Insulin Lispro are prescription medicines. For more information, call 1-800-545-5979.

This summary provides basic information about Humalog and Insulin Lispro Injection. It does not include all information known about these medicines. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other health care provider about your insulin lispro product and how to take it. Your doctor is the best person to help you decide if these medicines are right for you.


Humalog® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.


Humalog® (HU-ma-log) and Insulin Lispro Injection are fast-acting insulins used to control high blood sugar in adults and children with diabetes.

  • Humalog comes in two strengths: U-100 (100 units per milliliter) and U-200 (200 units per milliliter). The Humalog U-200 prefilled pen contains 2 times as much insulin per 1 milliliter as standard (U-100) insulin. The dose window on the pen shows your insulin dose.
  • It is not known if Humalog or Insulin Lispro Injection are safe and effective for children with type 2 diabetes or for children younger than 3 years of age with type 1 diabetes. There were no studies done with these insulins in these groups of children. If your doctor decides to give your child one of these insulins, he or she may give you special instructions.

All Humalog and Insulin Lispro Injection products contain insulin lispro.